Introduction About The Centre

MAC Centre, which stands for Medically Assisted Conception, was started in 1992. Currently, we are the leading Centre for infertility treatment in a Malaysian public hospital, performing 300 over IVF/ICSI cycles yearly or  10-15% of the total number of cases carried out nationwide.

 

MAC Center is a certified training centre for infertility that provides training to medical specialists, post-graduate medical doctors, embryologist, andrologists and nurses in Malaysia. As a reproductive centre  in a tertiary institution, we actively conduct research in assisted reproduction in order to improve the management of patients and to further our knowledge.

Staff

MAC has an excellent team of reproductive experts consisting of gynecologists, embryologists, andrologists, urologists, endocrinologists and geneticis. Our staff are leaders in their fields. They regularly travel throughout Malaysia to share their experience, teaching and training new personnel as well as providing expertise in newly set up laboratories.

To make your experience at MAC as comfortable, effortless and stress free as possible, your doctor will always attend to you personally at each stage of treatment. We will aid in determining the causes of infertility and assist you in achieving your goal with the best expertise and available resources.

For your ease of mind, there will always be nursing staff available for consultation. You will also meet the scientists who will be working with your doctor and nurses to guarantee the best care and support are yours throughout your time at MAC clinic

Inclusion Body

In our embryo lab, we often seen eggs with an inclusion body. Especially with patients' who had an endometriosis, pelvic inflammatory disease (PID), hydrosalphinx and polycyctic ovarian syndrome (PCOS). It always interrupting the fertilization of the egg. When we seen eggs with inclusion body, we already knew, that particular egg might not be fertilize. So, i did some research about what is actually "inclusion body" and how does it form. Here are some information about inclusion body that i manage to get from the Internet. 

According to Matt Bird in his article "Types and causes of inclusion bodies in human cells", inclusion body is an abnormal structural that appears in the cells. They're typically associated with proteins, and are sure signs of the presence of a virus or, in some extreme cases, genetic diseases. They are foreign invaders, and unwelcome in any living body. Inclusion bodies are typically identified within a cell both by their appearance under a microscope and, by connection, the practice of staining. How inclusion cells get into human cells varies from virus to virus and disease to disease, and in many cases it's yet unknown - or concretely known, anyway - how a person can wind up with inclusion bodies in their cells, and thus suffer the resulting consequences.

The nature of inclusion bodies is somewhat hinted at in the name: they're abnormal structures that build up in the nucleus or cytoplasm of cells, both human and animal. These structures, usually visible after staining and observation under a microscope, heavily hint at the presence of foul play in a cell, whether viral or genetic. Usually composed of protein, inclusion bodies are not a pleasant find and usually indicate current trouble or problems to come in a body. No wonder, patients' with an inclusion body would not fertilize.

According to Wikipedia, protein inclusion bodies are classically thought to contain misfolded protein. However, this has recently been contested, as green fluorescent protein will sometimes fluoresce in inclusion bodies, which indicates some resemblance of the native structure and researchers have recovered folded protein from inclusion bodies.